Faculty Directory

Xianghong Qian

Xianghong Qian

Professor

College of Engineering

(BMEG)-Biomedical Engineering

Phone: 479-575-8401

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Xianghong Qian is a full professor in the Department of Biomedical Engineering, College of Engineering.  Prior to joining UAF, she was a faculty member in the Department of Mechanical Engineering at Colorado State University. She has a BS degree in Chemistry from Nanjing University, China and a Ph.D. in Physical/Theoretical Chemistry from George Washington University, USA.  She did her postdoctoral research in Condensed Matter Theory at the Max-Planck Institute for Microstructure Physics, Germany. She also has experiences in industry and at a national laboratory before joining academia.

Dr. Qian’s major research interests focus on investigating the fundamental processes involved in carbohydrate chemistry, smart polymers for drug delivery and protein purifications, virus clearance, protein folding and misfolding using complementary experimental and theoretical and computational tools.  Ab initio and classical molecular dynamics simulation methods combined with static quantum mechanical calculations are used to elucidate the many underlying chemical and biochemical processes at the molecular level. She is the recipient of 2009 NSF CAREER award and has over 70 peer-reviewed journal articles and book chapter publications.

  • Postdoctoral Fellow, Max-Planck Institut für Mikrostrukturphysik, Halle, Germany, 1997-2000
  • Ph.D. Chemistry, George Washington University, 1997
  • M.Phil. Chemistry, George Washington University, 1994
  • B.S. Chemistry, Nanjing University, P.R. China, 1988

RECENT REFERRED JOURNAL ARTICLES

  • H. Himstedt, Q. Yang, L. P. Dasi, X. Qian, S.R. Wickramasinghe and M. Ulbricht, ‘Magnetically activated micro-mixing membranes’, Langmuir 27 (9), (2011) 5574-5581.
  • H. Du and X. Qian, ‘Molecular dynamics simulations of copolymer PNIPAM-co-PEGMA phase transition at lower critical solution temperature in NaCl solution’, Journal of Polymer Science Part B: Polymer Physics 49, (2011) 1112-1122.
  • H. Du and X. Qian, ‘The effects of acetate anion on cellulose dissolution and reaction in imidazolium ionic liquids’, Carbohydrate Research 346, (2011) 1985-1990.
  • X. Qian, ‘The mechanisms and energetics for glucose conversion to 5-hydroxymethylfurfurl’, Journal of Physical Chemistry A 115 (42), (2011) 11740-11748.
  • X. Qian (invited),‘Mechanisms and energetics for Brønsted acid−catalyzed glucose condensation, dehydration and isomerization reactions’, Topics in Catalysis 55(3-4), (2012) 218-226.
  • X. Wang, S. M. Husson, X. Qian, S. R. Wickramasinghe, ‘Inverse colloidal crystal ultrafiltration membranes’, Separation and Purification Technology 93, (2012) 33-41.
  • D. L. Grzenia, R. W. Dong, H. Jasuja, M. J. Kipper, X. Qian, S. R. Wickramasinghe, ‘Conditioning biomass hydrolysates by membrane extraction’, Journal of Membrane Science 415, (2012) 75-84.
  • X. Qian, X. F. Wei, ‘Glucose isomerization to fructose from ab initio molecular dynamics simulations’, Journal of Physical Chemistry B 116 (35), (2012) 10898-10904.
  • H. H. Himstedt, Q. Yang, X. Qian, S. R. Wickramasinghe, M. Ulbricht, ‘Toward remote-controlled valve functions via magnetically responsive capillary pore membranes’, Journal of Membrane Science 423–424, (2012) 257-266.
  • Q. Yang, H. H. Himstedt, M. Ulbricht, X. Qian, S.R. Wickramasinghe, ‘Designing magnetic field responsive nanofiltration membranes.’ Journal of Membrane Science 430, (2013) 70-78.
  • H. Du, S. R. Wickramasinghe, X. Qian, ‘Specificity in cationic interaction with poly (N-isopropylacrylamide)’, Journal of Physical Chemistry B 117, (2013) 5090-5101. 
  • H. H. Himstedt, H. Du, K. M. Marshall, S. R. Wickramasinghe, X. Qian,  ‘pH Responsive nanofiltration membranes for sugar separations’, Industrial & Engineering Chemistry Research 52 (26), (2013) 9259-9269.
  • H. H. Himstedt, X. Qian, J. R. Weaver, S. R. Wickramasinghe, ‘Responsive membranes for hydrophobic interaction chromatography’, Journal of Membrane Science 447, (2013) 335-344.
  • X. Qian, ‘Glucose transformation from the ring structure to the open chain form? an ab initio molecular dynamics investigation’, Journal of Physical Chemistry B 117, (2013) 11460-11465.
  • X. Qian, J. Lei, S. R. Wickramasinghe, ‘Novel polymeric solid acid catalysts for cellulose hydrolysis’, RSC Advances 3(46), (2013) 24280 - 24287.
  • X. Qian, D. Liu, ‘Free energy landscape for glucose condensation and dehydration reactions in dimethyl sulfoxide and the effects of solvent’, Carbohydrate Research 388, (2014) 50-60. 
  • Z. Liu, H. Du, S. R. Wickramasinghe, X. Qian, ‘Membrane surface engineering for protein separations: experiments and simulations’, Langmuir 30 (35), (2014) 10651-10660.
  • S. Darvishmanesh, X. Qian and S.R. Wickramasinghe, ‘Responsive membranes for advanced separations’, Current Opinion in Chemical Engineering 8, (2015) 98-104.
  • H. Du, X. Qian, ‘The hydration properties of carboxybetaine zwitterion brushes’, Journal of Computational Chemistry (2015), DOI: 10.1002/jcc.24234.
  • X. Qian, Q. Yang, A. Vu, S R. Wickramasinghe, ‘Localized Heat Generation from Magnetically Responsive Membranes’, Industrial & Engineering Chemistry Research 55, (2016) 9015-9027, DOI: 10.1021/acs.iecr.6b01820.
  • Z. Liu, S. R. Wickramasinghe, X. Qian, (invited) ‘Membrane Chromatography for Protein Purifications from Ligand Design to Functionalization’, Separation Science and Technology (2016), DOI:10.1080/01496395.2016.1223133.
  • H. Du, Z. Liu, R. Jennings, X. Qian, (invited) ‘The Effects of Salt Ions on the Dynamics and Thermodynamics of Lysozyme Unfolding’, Separation Science and Technology (2016), DOI:10.1080/01496395.2016.1229336.
  • A. Khang, P. Ravishankar, A. Krishnaswamy, P. Anderson, S. Cone; Z. Liu, X. Qian, K. Balachandran, ‘Engineering Anisotropic Biphasic Janus-type Polymer Nanofiber Networks via Centrifugal Jet Spinning’, Journal of Biomedical Materials B (2016), DOI: 10.1002/jbm.b.33791.

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